medicine contains the active ingredient apomorphine hydrochloride,
which is a type of medicine known as a dopamine agonist. It works
by enhancing the nerve signals that cause an erection.
An erection is produced via a complex chain of events. The process
is started with sexual stimulation from sight, smell, sound or
touch. This causes nerve signals to be sent from the brain to the
penis, which in turn cause the blood vessels in the penis to relax
and widen. This allows the penis to fill with blood and makes it
Apomorphine works by enhancing the nerve signals that are sent
from the brain to the penis during sexual stimulation.
It does this by mimicking the action of dopamine, which is a
natural chemical called a neurotransmitter. Neurotransmitters are
involved in sending signals along nerves. They act on special
receptor sites in the nervous system to produce their effects.
Dopamine acts on receptors called dopamine receptors, and this
causes nerve signals with various effects to be sent. When
dopamine acts on receptors in an area of the brain called the
hypothalamus, it causes the nerve signals that produce an erection
to be sent to the penis.
Apomorphine mimics the erection-producing effect of dopamine by
stimulating the same dopamine receptors in the hypothalamus. This
enhances the effect of natural dopamine that is produced as a
result of sexual stimulation. The nerve signals to the penis are
enhanced, and this results in blood entering the penis, ultimately
causing it to become rigid and erect.
As apomorphine enhances the action of dopamine in producing an
erection, it will only work once sexual stimulation has occurred.
It does not increase sex-drive (libido) and is not an aphrodisiac.
The sublingual tablet dissolves under the tongue, where it
immediately enters the bloodstream, causing an erection in most
sexually stimulated men in about 20 minutes.