This medicine contains
the active ingredient vardenafil, which is a medicine used in
the treatment of erectile dysfunction (impotence). Vardenafil
is called a phosphodiesterase type 5 inhibitor, and works by preventing
the action of a chemical in the body called phosphodiesterase
erection is produced via a complex chain of events, involving
signals from the nervous system and the release of chemical messengers
within the tissues of the penis. One of these chemical messengers
is called cyclic GMP.
GMP causes the blood vessels in the penis to widen by relaxing
a thin layer of muscle found in the blood vessel walls. This allows
more blood to enter the penis, which ultimately results in the
penis becoming rigid and erect.
GMP is normally broken down by another chemical in the body called
phosphodiesterase type 5. Vardenafil works by preventing the action
of phosphodiesterase type 5, thus stopping the breakdown of cyclic
GMP. This means that the blood vessels are kept dilated for longer,
improving blood flow to the penis and maintaining an erection.
vardenafil enhances the actions of the chemical messengers responsible
for producing an erection, it will only work once these messengers
are present. This means that sexual stimulation is required for
it to produce and maintain an erection. The dose should be taken
approximately 25 minutes to one hour before intended intercourse,
and it may produce an erection in response to sexual stimulation
up to five hours after taking the dose.